✔️ Two-way Action: FLYBEE amitraz kills bee mites by both touch and vapor. You can check that the efficacy is evident throughout the beehive.
✔️ High market acceptance: Beekeeping distributors who opt for this classic mite control solution gain consistent and dependable revenue earnings.
✔️ Large Capacity: Varroa treatment has its best season. Stock up once and stay worry-free for the whole cycle. This is true for large-scale apiaries with higher demand.
✔️ Eco-friendly Packaging: The 1-liter bottle uses less plastic packaging material than smaller bottles. For example, in some European countries with high environmental protection requirements, this is to reduce plastic waste.
Product Description
| Item | Details |
|---|---|
| Product Name | FLYBEE Amitraz Solution |
| Brand | APIBUZZ |
| Active Ingredient | Amitraz 12.5% EC |
| Packaging Size | 1 Liter per bottle |
| Shelf Life | 2 Years |
| Storage Conditions | Keep out of direct sunlight and keep sealed tightly |
| Eco-Aware Notice | Keep away from water sources, as amitraz can be toxic to fish |
Amitraz is a reliable solution used by beekeepers worldwide to combat varroa mites, the most destructive beekeeping pest today. It works by attacking the mite's nervous system and causing paralysis and death.
FLYBEE 1-liter amitraz solution provides commercial beekeepers and large-scale operations with a versatile, concentrated liquid varroa treatment engineered for maximum flexibility and cost-efficiency. The 12.5% emulsifiable concentrate (EC) formulation delivers proven mite control through both spray application and fumigation methods, offering adaptability to diverse climate conditions, seasonal requirements, and operational workflows that solid treatment strips cannot match.
During the rainy season, beekeepers have few options for mite control. In these humid climates, FLYBEE amitraz liquid works well. It has a long-lasting mite-killing effect. You can use the 1L large package on medium-sized to large bee farms.
Whether managing a medium-sized operation with 100-300 hives or a commercial enterprise with thousands of colonies, FLYBEE's bulk 1-liter packaging provides the treatment capacity and economic advantages that professional beekeepers demand for sustainable, year-round varroa management programs.Get more about FLYBEE 1 Liter 12.5% EC Amitraz.
Generally, there are two ways of using amitraz in beekeeping mite treatment.
| Method | Dilution | Per Hive | How to Apply | Frequency |
| Spray | Mix 2 ml in 1000 ml of water | 1000 ml per 200 frames | Spray lightly across the bee frames at a 45° angle | Every 3 days × 3–4 times |
| Vaporization | You don't need to dilute. Prepare a dropper at first. | 5 drops per 10-frame hive | Prepare the paper and dip drops of the solution on it. Ignite and smoke the beehive with a Varrojet. | Every 3 days × 3–4 times |
Important Tips:
Avoid applying amitraz below 10 °C or above 35 °C. Do not use it during the honey flow period. You must wear gloves and a mask to handle it. If you use the vaporization method, don't forget to wear goggles to avoid eye contact.
Standard Protocol:
Day 1: Initial application
Day 4: Second application
Day 7: Third application
Day 10: Fourth application (optional based on mite pressure)
Rationale for 3-Day Interval:Varroa reproductive cycle in sealed brood cells lasts 8-12 days. Repeated applications every 3 days ensure exposure to emerging mites as they exit cells, preventing population rebound.
Extended Protocol (High Mite Pressure):Continue treatments beyond 4 applications (up to 6-8 total) if:
Initial mite counts exceeded 5% infestation
Alcohol wash or sugar roll shows continued high mite levels
Visible mites on adult bees or drone brood
Amitraz demonstrates favorable selectivity between varroa mites and honeybees due to fundamental differences in nervous system architecture and detoxification capabilities.
Lethal Dose Comparison:
Varroa mites:
LD50 (lethal dose for 50% of population): 0.8 μg/mite
Honeybees:
LD50 (contact): 100 μg/bee
LD50 (oral): 24 μg/bee
Selectivity Ratio:The margin of safety (bee LD50 / mite LD50) exceeds 30:1 for contact exposure, indicating amitraz is substantially more toxic to mites than bees.
Practical Implications:When applied at label-recommended concentrations (0.025% for spray, pure concentrate for fumigation), amitraz provides effective mite control while remaining within safe exposure limits for adult bees.
Larval Sensitivity:Bee larvae show slightly higher sensitivity to amitraz than adults. However, field trials demonstrate no adverse effects on:
Larval survival rates
Pupal development
Adult emergence rates
Adult bee longevity from treated brood
Queens tolerate amitraz treatments without reproductive impairment. Long-term studies show:
No reduction in egg-laying rates
Normal sperm viability in drone offspring
No change in queen longevity
Stable pheromone production
Properly applied amitraz treatments cause no detectable:
Population declines
Foraging disruption
Honey production reductions
Increased absconding or swarming
Changes in defensive behavior
Before Application:
Check weather—wind speed should be <10 mph (16 km/h) to prevent drift
Post warning signs if treating near public access areas
Notify nearby beekeepers if within 1 mile
Ensure first aid kit accessible
Have clean water source available for eye/skin washing
During Application:
Mix and apply in well-ventilated outdoor area
Stand upwind of application site when possible
Avoid applying during peak foraging hours (reduces bee exposure at treatment moment)
Never eat, drink, or smoke while handling concentrate
If symptoms develop (dizziness, nausea, skin burning), cease application immediately and move to fresh air
After Application:
Wash hands and face thoroughly with soap and water
Launder contaminated clothing separately before reuse
Clean equipment with detergent and water
Store concentrate in original labeled container
Record treatment in hive management logs
F
First Aid Measures:
Skin Contact:
Remove contaminated clothing
Wash affected area with soap and water for 15 minutes
If irritation persists, seek medical attention
Eye Contact:
Rinse immediately with clean water for 15 minutes (hold eyelids open)
Remove contact lenses if present
Seek immediate medical attention (amitraz causes moderate eye irritation)
Inhalation:
Move to fresh air immediately
If breathing difficulties occur, administer oxygen if trained
Seek medical attention for persistent symptoms
Ingestion:
DO NOT induce vomiting
Rinse mouth with water
Drink 1-2 glasses of water to dilute
Seek immediate medical attention
Bring product label to medical facility
Never Under-Dose:Applying insufficient amitraz concentrations creates sublethal exposure that selects for resistant mites while killing susceptible individuals.
Correct Practices:
Measure dilutions precisely (use calibrated syringes, not estimates)
Follow label application rates exactly
Complete full treatment courses (don't stop at 2 applications if label requires 4)
Replace old product (amitraz degrades over time; use fresh concentrate)
Avoid Over-Dosing:While less likely to promote resistance, excessive dosing:
Increases bee exposure and potential stress
Wastes product (no additional efficacy beyond label rates)
Elevates honey/wax residues unnecessarily
Pre-Treatment Mite Counts:
Conduct alcohol wash or sugar roll before initiating treatment
Establish baseline infestation percentage
Document in treatment records
Post-Treatment Evaluation:
Re-count mites 14-21 days after final application
Calculate percentage reduction: [(Pre-count - Post-count) / Pre-count] × 100
Expected Efficacy Standards:
Susceptible populations: 90-98% reduction
Declining efficacy: 70-85% reduction (warning sign)
Resistance suspected: <70% reduction (investigate further)
Response to Reduced Efficacy:
If post-treatment counts show <80% reduction:
Rule out application errors (incorrect dilution, missed applications, wrong timing)
Increase treatment frequency (5-6 applications instead of 4)
Switch to alternative active ingredient immediately (don't persist with failing treatment)
Consider resistance testing (send samples to research labs offering bioassay services)
Implement intensive rotation (avoid amitraz for 2-3 years minimum)
Concentrated Product Storage:
Storage Conditions:
Temperature: 15-25°C (59-77°F) optimal
Avoid temperature extremes (do not freeze; keep below 40°C/104°F)
Store in original container (HDPE plastic compatible with amitraz)
Protect from direct sunlight (UV degradation)
Keep container tightly sealed (prevents oxidation)
Shelf Life:
Manufacturer specification: 2 years from production date
Stored under ideal conditions: Maintains 95%+ potency for 2 years
After 2 years: Gradual potency decline (5-10% loss per additional year)
Stability Indicators:
Product Remains Good:
Clear to pale yellow liquid
No particulate matter or sediment
No unusual odor (amitraz has mild characteristic odor)
Product Degraded:
Dark brown or black discoloration
Thick sediment or crystals at bottom
Strong chemical or rancid odor
Separated layers that won't re-mix with shaking
If degradation suspected: Discard product and purchase fresh concentrate.
FLYBEE 1-liter amitraz solution delivers the operational flexibility, economic efficiency, and proven efficacy that medium to large beekeeping operations demand. The dual-capability formulation—supporting both spray and fumigation applications—provides strategic options to adapt treatment approaches to changing weather conditions, seasonal requirements.
Package Includes:
1 liter (1000ml) FLYBEE 12.5% EC amitraz concentrate
Complete application instructions for spray and fumigation methods
Safety guidelines and PPE recommendations
Dilution calculation chart
Product Details




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